Cardiac Resynchronization Therapy (CRT) in a Patient With With Chronic Kidney Disease, Diabetes and Hypertension

Dr. S. A. Merchant | Advanced Heart Failure Clinic in Mumbai

Patient Profile

NameConfidential
Age50 years
GenderMale
OccupationPolice constable
Presenting ComplaintsAbdominal distension, dyspnea on exertion, fatigue
Key Investigation FindingsHigh creatinine, high HbA1c
DiagnosisChronic Kidney Disease (CKD), Diabetes Mellitus, Hypertension
TreatmentCRT implant (23 March 2026), Guideline-Directed Medical Therapy (GDMT)
OutcomeStable on GDMT
Long-Term PlanRenal diet as advised, to decrease creatinine levels
Patient details shared for this case study; identity referred to by name as provided for the record.

The Problem

Condition

The patient, a 50-year-old male working as a police constable, consulted Dr. S. A. Merchant at the Advanced Heart Failure Clinic with abdominal distension, dyspnea on exertion, and fatigue. Dyspnea on exertion refers to breathlessness during physical activity, and abdominal distension refers to swelling or fullness of the abdomen. Both can be associated with fluid retention, and fatigue is a common accompanying symptom.

Laboratory evaluation showed a high serum creatinine and a high HbA1c. These findings, together with the clinical assessment, established diagnoses of Chronic Kidney Disease (CKD), Diabetes Mellitus, and Hypertension. The patient subsequently underwent a CRT implant on 23 March 2026 and is being managed on Guideline-Directed Medical Therapy (GDMT).

Understanding the Findings

Serum creatinine is a waste product filtered by the kidneys. A raised level indicates reduced kidney filtration and is one of the markers used to assess kidney function. HbA1c reflects average blood glucose control over the preceding two to three months, and a high value indicates that glucose levels have remained above target.

Diabetes mellitus and hypertension are both recognized contributors to chronic kidney disease. The heart and kidneys also influence one another, since changes in cardiac function can affect blood flow to the kidneys, and reduced kidney function can affect fluid balance and blood pressure. For this reason, the management of a patient with cardiac symptoms alongside CKD, diabetes, and hypertension requires attention to all three conditions together.

Consultation and Treatment Plan

Why This Approach Was Chosen

Dr. S. A. Merchant advised a CRT implant together with GDMT. This approach addresses the cardiac component of the patient’s condition through device therapy and medication, while the associated kidney, glucose, and blood pressure findings are taken into account in the overall plan.

A renal diet was also advised, with the aim of decreasing creatinine levels. This reflects a general principle in patients with CKD, where dietary measures form part of the long-term management alongside medical treatment.

Procedure Details

Overview

The patient’s management combined a CRT implant with Guideline-Directed Medical Therapy and dietary guidance.

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Approach:

CRT implantation (23 March 2026) combined with GDMT and a renal diet
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Systems addressed:

Cardiac function and symptoms (abdominal distension, exertional dyspnea, fatigue), with dietary guidance directed at kidney function
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Associated finding:

Chronic Kidney Disease, Diabetes Mellitus, Hypertension
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Cardiologist:

Dr. S. A. Merchant

CRT Implant

Cardiac Resynchronization Therapy (CRT) is a device-based treatment used in selected patients with heart failure. The device is implanted under the skin, with leads placed in the heart, and delivers timed electrical impulses that help the chambers of the heart contract in a more coordinated manner. A coordinated contraction can improve the efficiency with which the heart pumps blood. In this patient, the CRT implant was carried out on 23 March 2026.

Guideline-Directed Medical Therapy

Guideline-Directed Medical Therapy (GDMT) refers to the combination of medications recommended by clinical guidelines for the treatment of heart failure. The aim is to reduce symptoms and the risk of worsening heart failure. In patients with kidney disease, the choice and dose of medication are individualized by the treating cardiologist, since kidney function can influence how medicines are tolerated and cleared from the body. The patient continues on GDMT.

Renal Diet

A renal diet is a dietary plan designed to reduce the load on the kidneys. The specific restrictions differ between patients and depend on the stage of kidney disease, laboratory results, and other conditions such as diabetes and hypertension. For this patient, a renal diet was advised to decrease creatinine levels, and the patient has been counselled to follow it as directed.

Post-Treatment Results

Following the CRT implant and with ongoing GDMT, the patient is stable. His care continues under Dr. S. A. Merchant at the Advanced Heart Failure Clinic.

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Current medical therapy

Stable on GDMT
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Dietary guidance

Renal diet as advised
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Patient satisfaction

Satisfied
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Device therapy

CRT implanted on 23 March 2026
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Long-term plan

Adherence to the renal diet to decrease
creatinine levels

Long-Term Follow-Up

Long-term management of this patient centres on continued GDMT and adherence to the advised renal diet, with the aim of decreasing creatinine levels. Regular review allows the treating team to monitor cardiac status, kidney function, and glucose and blood pressure control, and to adjust treatment as required.

Patient Feedback

The patient reported being satisfied with his care.

Profile: Male · 50 years · Police constable Management: CRT Implant · Guideline-Directed Medical Therapy · Renal Diet Cardiologist: Dr. S. A. Merchant, Advanced Heart Failure Clinic, Bandra West, Mumbai

Frequently Asked Questions

Q1. What is Cardiac Resynchronization Therapy (CRT)?

CRT is a device-based treatment in which an implanted device delivers timed electrical impulses so that the chambers of the heart contract in a more coordinated manner.

Q2. What does Guideline-Directed Medical Therapy (GDMT) mean?

GDMT is the combination of medications recommended by clinical guidelines for heart failure. It aims to reduce symptoms and the risk of worsening heart failure.

Q3. Why was a renal diet advised for this patient?

The patient has Chronic Kidney Disease with a high creatinine level. A renal diet was advised to help decrease creatinine levels.

Q4. How are heart and kidney conditions related?

The heart and kidneys influence each other. Changes in cardiac function can affect blood flow to the kidneys, and reduced kidney function can affect fluid balance and blood pressure.

Q5. What is the patient's current status?

The patient is stable on GDMT following the CRT implant on 23 March 2026, and continues to follow the advised renal diet.

Q6. Why choose Dr. S. A. Merchant?

He is an Advanced Heart Failure specialist in Mumbai, with a focus on device therapy, guideline-directed medical management, and heart transplant evaluation for patients with advanced heart disease.

Living With Heart Symptoms and Kidney Disease?

A consultation at the Advanced Heart Failure Clinic in Mumbai gives you the chance to understand your condition and which treatment options are realistic for you.

Disclaimer:The information on this page is for general informational purposes only and is not a substitute for professional medical advice, diagnosis or treatment. Individual results vary from patient to patient. Always consult a qualified cardiologist regarding any medical condition.

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